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isca2 antibody  (Atlas Antibodies)


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    Structured Review

    Atlas Antibodies isca2 antibody
    <t>ISCA2</t> was upregulated and significantly correlated with HNSC progression (A) Univariate Cox regression analysis of CRGs (B , C) Boxplot showing ISCA2 expression in TCGA-first (B) and TCGA-second (C) cohorts (D) Validation of ISCA2 expression by IHC in HNSC and normal tissues (E) Univariate Cox regression analysis of clinical features (F) Multivariate Cox regression analysis of risk factors consisting of ISCA2, gender, age pathologic stage, and alcohol history (G–I) Kaplan-Meier curve showing the association of ISCA2 expression with the 5-year OS (G) , PFI (H) , and DSS (I,J) Association of ISCA2 with the OS in all TCGA HNSC samples as verified GEPIA2 webserver. ****p-value < 0.0001.
    Isca2 Antibody, supplied by Atlas Antibodies, used in various techniques. Bioz Stars score: 94/100, based on 2 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/isca2/Anti-ISCA2/pmc09845781-46-1-8
    Average 94 stars, based on 2 article reviews
    isca2 antibody - by Bioz Stars, 2026-09
    94/100 stars

    Images

    1) Product Images from "An original cuproptosis-related genes signature effectively influences the prognosis and immune status of head and neck squamous cell carcinoma"

    Article Title: An original cuproptosis-related genes signature effectively influences the prognosis and immune status of head and neck squamous cell carcinoma

    Journal: Frontiers in Genetics

    doi: 10.3389/fgene.2022.1084206

    ISCA2 was upregulated and significantly correlated with HNSC progression (A) Univariate Cox regression analysis of CRGs (B , C) Boxplot showing ISCA2 expression in TCGA-first (B) and TCGA-second (C) cohorts (D) Validation of ISCA2 expression by IHC in HNSC and normal tissues (E) Univariate Cox regression analysis of clinical features (F) Multivariate Cox regression analysis of risk factors consisting of ISCA2, gender, age pathologic stage, and alcohol history (G–I) Kaplan-Meier curve showing the association of ISCA2 expression with the 5-year OS (G) , PFI (H) , and DSS (I,J) Association of ISCA2 with the OS in all TCGA HNSC samples as verified GEPIA2 webserver. ****p-value < 0.0001.
    Figure Legend Snippet: ISCA2 was upregulated and significantly correlated with HNSC progression (A) Univariate Cox regression analysis of CRGs (B , C) Boxplot showing ISCA2 expression in TCGA-first (B) and TCGA-second (C) cohorts (D) Validation of ISCA2 expression by IHC in HNSC and normal tissues (E) Univariate Cox regression analysis of clinical features (F) Multivariate Cox regression analysis of risk factors consisting of ISCA2, gender, age pathologic stage, and alcohol history (G–I) Kaplan-Meier curve showing the association of ISCA2 expression with the 5-year OS (G) , PFI (H) , and DSS (I,J) Association of ISCA2 with the OS in all TCGA HNSC samples as verified GEPIA2 webserver. ****p-value < 0.0001.

    Techniques Used: Expressing, Biomarker Discovery

    Expression validation of genes in 12-CRGs signature using RNA-Seq data of LSCC and ANM tissues (A–F) Expression levels of NTHL1 (A) , DNA2 (B) , DLAT (C) , ISCA2 (D) , MTFR1L (E) and POLE (F) .
    Figure Legend Snippet: Expression validation of genes in 12-CRGs signature using RNA-Seq data of LSCC and ANM tissues (A–F) Expression levels of NTHL1 (A) , DNA2 (B) , DLAT (C) , ISCA2 (D) , MTFR1L (E) and POLE (F) .

    Techniques Used: Expressing, Biomarker Discovery, RNA Sequencing

    Related Articles

    Staining:

    Article Title: ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma.
    Article Snippet: .. TMAs and tissue were stained for ISCA2 (HPA030492 Atlas antibodies, Bromma, Sweden) using conditions optimized using normal kidney according to the manufacturer’s protocols using the BenchMark Ultra automated slide stainer (Ventana Medical Systems, Roche, Oro Valley, AZ). ..

    Article Title: ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma
    Article Snippet: .. TMAs and tissue were stained for ISCA2 (HPA030492 Atlas antibodies, Bromma, Sweden) using conditions optimized using normal kidney according to the manufacturer’s protocols using the BenchMark Ultra automated slide stainer (Ventana Medical Systems, Roche, Oro Valley, AZ). .. P-values, curve fitting and IC 50 calculations, Kaplan Meier plots (with logrank p-values and hazard ratios) were determined using Prism Version 9.3.1 (GraphPad Software, San Diego).

    Article Title: ISCA2 inhibition decreases HIF and induces ferroptosis in clear cell renal carcinoma
    Article Snippet: .. TMAs and tissue were stained for ISCA2 (HPA030492 Atlas antibodies, Bromma, Sweden) using conditions optimized using normal kidney according to the manufacturer’s protocols using the BenchMark Ultra automated slide stainer (Ventana Medical Systems, Roche, Oro Valley, AZ). ..



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    <t>ISCA2</t> was upregulated and significantly correlated with HNSC progression (A) Univariate Cox regression analysis of CRGs (B , C) Boxplot showing ISCA2 expression in TCGA-first (B) and TCGA-second (C) cohorts (D) Validation of ISCA2 expression by IHC in HNSC and normal tissues (E) Univariate Cox regression analysis of clinical features (F) Multivariate Cox regression analysis of risk factors consisting of ISCA2, gender, age pathologic stage, and alcohol history (G–I) Kaplan-Meier curve showing the association of ISCA2 expression with the 5-year OS (G) , PFI (H) , and DSS (I,J) Association of ISCA2 with the OS in all TCGA HNSC samples as verified GEPIA2 webserver. ****p-value < 0.0001.
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    Image Search Results


    ISCA2 was upregulated and significantly correlated with HNSC progression (A) Univariate Cox regression analysis of CRGs (B , C) Boxplot showing ISCA2 expression in TCGA-first (B) and TCGA-second (C) cohorts (D) Validation of ISCA2 expression by IHC in HNSC and normal tissues (E) Univariate Cox regression analysis of clinical features (F) Multivariate Cox regression analysis of risk factors consisting of ISCA2, gender, age pathologic stage, and alcohol history (G–I) Kaplan-Meier curve showing the association of ISCA2 expression with the 5-year OS (G) , PFI (H) , and DSS (I,J) Association of ISCA2 with the OS in all TCGA HNSC samples as verified GEPIA2 webserver. ****p-value < 0.0001.

    Journal: Frontiers in Genetics

    Article Title: An original cuproptosis-related genes signature effectively influences the prognosis and immune status of head and neck squamous cell carcinoma

    doi: 10.3389/fgene.2022.1084206

    Figure Lengend Snippet: ISCA2 was upregulated and significantly correlated with HNSC progression (A) Univariate Cox regression analysis of CRGs (B , C) Boxplot showing ISCA2 expression in TCGA-first (B) and TCGA-second (C) cohorts (D) Validation of ISCA2 expression by IHC in HNSC and normal tissues (E) Univariate Cox regression analysis of clinical features (F) Multivariate Cox regression analysis of risk factors consisting of ISCA2, gender, age pathologic stage, and alcohol history (G–I) Kaplan-Meier curve showing the association of ISCA2 expression with the 5-year OS (G) , PFI (H) , and DSS (I,J) Association of ISCA2 with the OS in all TCGA HNSC samples as verified GEPIA2 webserver. ****p-value < 0.0001.

    Article Snippet: The ISCA2 antibody used for immunohistochemistry was HPA030492 (Atlas antibodies, Bromma, Sweden).

    Techniques: Expressing, Biomarker Discovery

    Expression validation of genes in 12-CRGs signature using RNA-Seq data of LSCC and ANM tissues (A–F) Expression levels of NTHL1 (A) , DNA2 (B) , DLAT (C) , ISCA2 (D) , MTFR1L (E) and POLE (F) .

    Journal: Frontiers in Genetics

    Article Title: An original cuproptosis-related genes signature effectively influences the prognosis and immune status of head and neck squamous cell carcinoma

    doi: 10.3389/fgene.2022.1084206

    Figure Lengend Snippet: Expression validation of genes in 12-CRGs signature using RNA-Seq data of LSCC and ANM tissues (A–F) Expression levels of NTHL1 (A) , DNA2 (B) , DLAT (C) , ISCA2 (D) , MTFR1L (E) and POLE (F) .

    Article Snippet: The ISCA2 antibody used for immunohistochemistry was HPA030492 (Atlas antibodies, Bromma, Sweden).

    Techniques: Expressing, Biomarker Discovery, RNA Sequencing